Onyx Pharmaceutical shares are off 10c to $20.65 and option volume is 6x the daily average being driven by spread of the Aug. $30/40 call spread which traded 3,100x at 3c. This is likely closing a position 5/11 when shares were around $25 having already gapped down 5/4 following a disappointing earnings report. The biotech company has been a frequent mentioned as a takeover target in recent years but nothing of substance has ever materialized.